Radiation enhanced gene therapy for tumors expressing a gene for a viral pyrimidine kinase in the presence of a 5′-halogenated pyrimidine
US6342217B1 · kind B1 · utility
4Cited by
6References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 21, 1999 |
| Grant date | Jan 29, 2002 |
| Priority date | — |
| Expiry date | Jul 21, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention pertains to combination radio therapy of tumors and more specifically to pharmaceutical compositions, and methods of treatment by gene therapy designed to sensitize tumors in animals, notably humans, and render them more susceptible to radiation, thus significantly reducing the amount of radiation required to kill neoplastic cells while at the same time making the radiation far more tissue specific to the tumor site.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.