Death domain containing receptor 4 nucleic acids and methods
US6342363B1 · kind B1 · utility
29Cited by
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303Claims
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Assignee
Inventors
Key dates
| Filing date | Jan 27, 1998 |
| Grant date | Jan 29, 2002 |
| Priority date | — |
| Expiry date | Jan 27, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/70578
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.