Method of treating estrogen receptor positive carcinoma with 17 &agr;-dihydroequilin
US6342491B1 · kind B1 · utility
61Cited by
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18Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 10, 1992 |
| Grant date | Jan 29, 2002 |
| Priority date | — |
| Expiry date | Nov 10, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/567
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides a method of treating estrogen receptor positive carcinoma in a mammal in need thereof which comprises administering an antineoplastic amount of 17&agr;-dihydroequilin or a mammalian metabolic conjugate thereof orally, parenterally, transdermally, topically, rectally, intravaginally, intranasally, or intrabronchially. As such, the compounds of this invention are useful in treating estrogen receptor positive carcinomas such as carcinomas of the breast, uterus, ovary, fallopian tube, cervix, vagina, liver, pituitary, central nervous system, hypothalamus, bone, skin, kidney, urethra, prostate, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.