Patent · US Expired

3,4,5-trisubstituted aryl nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation

US6342523B1 · kind B1 · utility

9Cited by
46References
38Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 1, 1999
Grant dateJan 29, 2002
Priority date
Expiry dateDec 1, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have the formula: where R1-R4 are as defined in the specification. The disclosed compositions are useful as therapeutics for inflammation-related conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.