Subtle mitochondrial mutations as tumor markers
US6344322B1 · kind B1 · utility
21Cited by
8References
27Claims
0Family size
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Key dates
| Filing date | Aug 20, 1999 |
| Grant date | Feb 5, 2002 |
| Priority date | — |
| Expiry date | Aug 20, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The accumulation of homoplasmic somatic mutations has been observed in the mitochondrial DNA of certain tumor cells. The presence or recurrence of a tumor can be detected by determining the presence of single basepair mutations in the mitochondrial genome from a cell sample of a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.