Methods for analysis and sorting of polynucleotides
US6344325B1 · kind B1 · utility
184Cited by
98References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2000 |
| Grant date | Feb 5, 2002 |
| Priority date | — |
| Expiry date | Feb 8, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S366/03
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a microfabricated device and methods of using the device for analyzing and sorting individual polynucleotides, e.g., by size according to an optical signal measured within a detection region of the device. An optical signal such as fluorescence from a reporter molecule associated with the polynucleotide molecules can be used to determine polynucleotide size or to direct selected polynucleotides into one or more selected branch channels of the device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.