Conductance of improperly folded proteins through the secretory pathway
US6344475B1 · kind B1 · utility
29Cited by
10References
48Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 27, 1999 |
| Grant date | Feb 5, 2002 |
| Priority date | — |
| Expiry date | Oct 27, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91102
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particuarly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.