Patent · US Expired

Biodegradable ionic matrix of variable internal polarity with grafted polymer

US6346263B1 · kind B1 · utility

4Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 14, 2000
Grant dateFeb 12, 2002
Priority date
Expiry dateMar 14, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/5036
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a particulate biodegradable matrix comprising a biodegradable and hydrophilic core with a base of carbohydrate or polyol or polyamine matrix, cross-linked and derived in the mass by variable amounts of ionic groups; a hydrophilic polymer layer associated with the central core by chemical, for example ionic, interaction; and surface molecules or polymers grafted on the external polymer layer by covalent bonds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.