Patent · US Expired

Sustained release formulation containing three different types of polymers and tablet formed therefrom

US6346268B1 · kind B1 · utility

6Cited by
27References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 21, 2000
Grant dateFeb 12, 2002
Priority date
Expiry dateJan 21, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/2054
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) a pH dependent gelling polymer such as an alginate component, (2) an enteric polymer component, such as Eudragit® L or S, and (3) a pH independent gelling polymer, such as hydroxy propyl methyl cellulose or polyethylene oxide. The drug release rate can be adjusted by changing the amount of one or more of these components of the composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.