Patent · US Expired

Process for the pasteurization of plasma or concentrates of blood coagulation factors II, VII, IX and X

US6346277B1 · kind B1 · utility

2Cited by

10References

17Claims

0Family size

Assignee

Aventis Behring GmbH · DE

Inventors

Norbert Heimburger
Gerhardt Kumpe · Wetter, DE
Wilfried Wormsbacher · Kirchhain, DE
Hans M. Preis · Marburg, DE

Key dates

Filing date	Mar 31, 1995
Grant date	Feb 12, 2002
Priority date	—
Expiry date	Mar 31, 2015

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a process for the preparation of a product of blood coagulation factors II, VII, IX and X which is virtually free of virus, the process comprising heating an aqueous liquid containing these factors in the presence of calcium ions and a chelating agent and, optionally, an amino acid, a saccharide or sugar alcohol, antithrombin III and/or heparin. The product can be used for the treatment of blood coagulation disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.