Process for the preparation of C-4 deacetyltaxanes
US6348337B1 · kind B1 · utility
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5Claims
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Key dates
| Filing date | Aug 17, 2000 |
| Grant date | Feb 19, 2002 |
| Priority date | — |
| Expiry date | Aug 17, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P15/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process useful for the preparation of intermediates in synthesis or semi-synthesis of paclitaxel analogs wherein a starting taxane such as 10-deacetylbaccatin III is deacetylated at the C-4 position using a microorganism or an enzyme derived therefrom to provide 4-deacetyltaxanes, such as 4,10-dideacetylbaccatin III.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.