Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same
US6348344B1 · kind B1 · utility
18Cited by
2References
95Claims
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Key dates
| Filing date | Mar 2, 1999 |
| Grant date | Feb 19, 2002 |
| Priority date | — |
| Expiry date | Mar 2, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2400/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.