Patent · US Expired

NPY antagonists: spiroisoquinolinone derivatives

US6348472B1 · kind B1 · utility

5Cited by
5References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 2, 2000
Grant dateFeb 19, 2002
Priority date
Expiry dateJun 2, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of spiroisoquinolinone derivatives of Formula I. As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.