Sulfonamide compounds and medicinal use thereof
US6348474B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 14, 2000 |
| Grant date | Feb 19, 2002 |
| Priority date | — |
| Expiry date | Feb 14, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A sulfonamide compound of the formula (I):R1—SO2NHCO—A—R2  (I)wherein R1 is alkyl, alkenyl, alkynyl and the like; A is an optionally substituted heteropolycyclic group except benzimidazolyl, indolyl, 4,7-dihydrobenzimidazolyl and 2,3-dihydrobenzoxazinyl; X is alkylene, oxa, oxa(lower)alkylene and the like; and R2 is optionally substituted aryl, substituted biphenylyl and the like, a salt thereof and a pharmaceutical composition comprising the same. The sulfonamide compound is effective for the diseases treatable based on their blood sugar level-depressing activity, cGMP-PDE (especially PDE-V)-inhibiting activity, smooth muscle relaxing activity, bronchodilating activity, vasodilating activity, smooth muscle cell suppressing activity, and antiallergic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.