Patent · US Expired

High affinity humanized anti-TAG-72 monoclonalantibodies

US6348581B1 · kind B1 · utility

13Cited by
12References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 18, 1998
Grant dateFeb 19, 2002
Priority date
Expiry dateFeb 18, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/24
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Novel humanized monoclonal antibodies, humanized antibody fragments, and derivatives thereof which specifically bind TAG-72 are provided as well as methods for their manufacture. These humanized antibodies are useful in the treatment of cancers which express TAG-72 as well as for diagnostic purposes, e.g., for in vivo imaging of tumors or cancer cells which express TAG-72.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.