Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6350456B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 7, 1998 |
| Grant date | Feb 26, 2002 |
| Priority date | — |
| Expiry date | Apr 7, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods for treatment and vaccination against tuberculosis are disclosed. In one aspect the compositions provided include at least two polypeptides that contain an immunogenic portion of a M. tuberculosis antigen or at least two DNA molecules encoding such polypeptides. In a second aspect, the compositions provided include a fusion protein comprising at least two polypeptides that contain an immunogenic portion of a M. tuberculosis antigen. Such compositions may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.