Mixed micellar drug deliver system and method of preparation
US6350458B1 · kind B1 · utility
88Cited by
13References
31Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 6, 2000 |
| Grant date | Feb 26, 2002 |
| Priority date | — |
| Expiry date | Apr 6, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in micellar form are disclosed. The micelles are formed from an alkali metal alkyl sulfate, and at least one additional micelle-forming compound as described in the specification. An alkali metal salicylate and a pharmaceutically acceptable edetate are also included in the composition. Micelle size ranges between about 1 and 10 nanometers. Methods for making and using the compositions are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.