Patent · US Expired

Beta-carboline compounds

US6350757B1 · kind B1 · utility

24Cited by
1References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 21, 2000
Grant dateFeb 26, 2002
Priority date
Expiry dateJul 21, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/28
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A compound selected from those of formula (I): wherein:<CUSTOM-CHARACTER FILE="US06350757-20020226-P00900.TIF" ALT="custom character" HE="20" WI="20" ID="CUSTOM-CHARACTER-00001"/> represents single or double bond,R1 represents hydrogen, alkyl, &#8212;R6-aryl, &#8212;R6-cycloalkyl, &#8212;R6-heterocycle, &#8212;CO2R7&#8212;, &#8212;COR8, or &#8212;CONHR8, wherein R6, R7, and R8 are as defined in the description,R2 represents cyano, mono- or di-alkylaminoalkylaminocarbonyl, &#8212;CO2R8, &#8212;CONHR8, &#8212;NR8R9, &#8212;NHCO2R7, or &#8212;COR8 wherein R7, R8, and R9 are as defined in the description,R3 and R4 together form (C3-C10)cycloalkyl,R5 represents hydrogen, alkyl, or arylalkyl,Ra, Rb, Rc, Rd, which may be identical or different, represent a group as defined in the description,its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same which are useful in the treatment of CNS disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.