Antithrombotic agents

US6350774B1 · kind B1 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Nicholas J. Bach · Indianapolis, US
• Jolie Ann Bastian · Beech Grove, US
• Nickolay Y Chirgadze · Carmel, US
• Michael Lyle Denney · Franklin, US
• Robert J. Foglesong · Durham, US
• Richard Waltz Harper · Indianapolis, US
• Mary G. Johnson · Carrboro, US
• Ho-Shen Lin · Indianapolis, US
• Michael P Lynch · Raleigh, US
• Jefferson Ray McCowan · Indianapolis, US
• Alan David Palkowitz · Carmel, US
• Daniel Jon Sall · Greenwood, US
• Gerald Floyd Smith · Indianapolis, US
• Kumiko Takeuchi · Indianapolis, US
• Minsheng Zhang · Hackettstown, US

Key dates

• Filing date: Jan 24, 2000
• Grant date: Feb 26, 2002
• Expiry date: Jan 24, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This application relates to novel compounds of formula (I) (and their pharmaceutically acceptable salts), as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula (I), and the use of the compounds of formula (I) as thrombin inhibitors.