Trifluoromethyl ketone analogs as selective cPLA2 inhibitors
US6350892B1 · kind B1 · utility
7Cited by
4References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 18, 2000 |
| Grant date | Feb 26, 2002 |
| Priority date | — |
| Expiry date | Feb 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/2458
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Selective inhibitors of the cPLA2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where (R′), p, D, Y, Z, Ra, Rb and A are as defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.