Electrochemical system for determining blood coagulation time
US6352630B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2000 |
| Grant date | Mar 5, 2002 |
| Priority date | — |
| Expiry date | Feb 8, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/974
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Electrochemical system for measuring a value representing the coagulation time of a drop of whole blood including:an electrochemical sensor in the shape of a strip of small dimensions bearing at least a reference electrode and a working electrode on which a specific reagent is immobilized, including at least one chemical substrate one terminal link of which can be cut off by the thrombin enzyme to give charged groups (LG), anda measuring apparatus intended to receive said sensor allowing a given voltage or current to be imposed across the electrodes of the sensor, the electric signal resulting from the migration of the charged groups to be processed, said signal to be correlated with a value representing the coagulation time, and said value to be displayed on a display panel.The specific reagent preferably includes an oligopeptidic derivative as a substrate, a thromboplastin and a buffer medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.