Patent · US Expired

Steroidal liposomes

US6352716B1 · kind B1 · utility

33Cited by
35References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 18, 1993
Grant dateMar 5, 2002
Priority date
Expiry dateAug 18, 2013

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T428/2984
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to bompositions comprising a mixtue of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.