Prostate cancer assays and related methods
US6352834B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1998 |
| Grant date | Mar 5, 2002 |
| Priority date | — |
| Expiry date | Jul 17, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/962
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention includes a method for stimulating increased PSA production by prostate cancer cells, comprising the steps of reducing the amount of iron available to the prostate cancer cells; and causing increased PSA production. In another aspects of the present invention, there are provided prostate cancer diagnostic kits comprising a first container containing an iron chelator; and second container containing a free-PSA-specific antibody, wherein the free-PSA-specific antibody is detectable. Also provided as part of the present invention are methods for diagnosing prostate cancer in a human, comprising reducing the amount of available iron in the human, and subsequently testing PSA levels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.