Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

US6353006B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Brian R. Dixon · Woodbridge, US
• Cedo Martin Bagi · Branford, US
• Catherine Brennan · Durham, US
• David R. Brittelli · Branford, US
• William Bullock · Easton, US
• Jinshan Chen · Madison, US
• William Collibee · Bethany, US
• Robert Dally · Indianapolis, US
• Jeffrey Johnson · Branford, US
• Harold C. Kluender · Madison, US
• William F. LATHROP · Plantsville, US
• Peiying Liu · Madison, US
• Carol Ann Mase · Ringoes, US
• Aniko Redman · Derby, US
• William Scott · Guilford, US
• Klaus Urbahns · Kasai, JP
• Donald J. Wolanin · Orange, US

Key dates

• Filing date: Dec 3, 1999
• Grant date: Mar 5, 2002
• Expiry date: Dec 3, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.