Process of use in converting the 4″(S)-OH functional group of the cladinose unit of an azamacrolide to 4″(R)-NH2
US6353096B1 · kind B1 · utility
2Cited by
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32Claims
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Assignee
Inventors
Key dates
| Filing date | Jan 18, 2000 |
| Grant date | Mar 5, 2002 |
| Priority date | — |
| Expiry date | Jan 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The subject-matter of the invention is a process for the stereoselective preparation of a compound of general formula I by stereoselective displacement by a nitrogenous nucleophilic compound of the activated alcohol functional group present at this 4″ position in a corresponding derivative of formula II.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.