Method for producing triazolinethione derivatives

US6353114B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Manfred Jautelat · Burscheid, DE
• David Erdman · Neunburg vorm Wald, DE

Key dates

• Filing date: Dec 27, 2000
• Grant date: Mar 5, 2002
• Expiry date: Dec 27, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D249/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

According to a novel process, triazolinethione derivatives of the formula in which R1 and R2 are each as defined in the description,can be prepared bya) reacting hydrazine derivatives of the formula  with formaldehyde and thiocyanate of the formulaX—SCN  (III), in whichX represents sodium, potassium or ammonium, in the presence of a diluent and if appropriate in the presence of an acid, andb) reacting the resulting triazolidinethiones of the formula  either&agr;) with oxidizing agents, if appropriate in the presence of a catalyst and in the presence of a diluent, or&bgr;) with formic acid.The triazolidinethiones of the formula (IV) are novel.