Process for the adiabatic preparation of 3,4-dichloronitrobenzene

US6353142B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Eberhard Zirngiebl
• Bernd-Michael Konig · Düsseldorf, DE
• Hans-Martin Weber · Leverkusen, DE
• Thomas Linn · Grevenbroich, DE
• Hans-Joachim Raatz · Leverkusen, DE

Key dates

• Filing date: Nov 2, 2000
• Grant date: Mar 5, 2002
• Expiry date: Nov 2, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C201/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

1,2-Dichlorobenzene can be reacted very selectively under adiabatic reaction conditions to give 3,4-dichloronitrobenzene by intensively mixing 1,2-dichlorobenzene with nitric acid, sulphuric acid and water, simultaneously or successively, in their total amount, using a mixing energy of 1-50 watts per litre of the total reaction mixture, preferably 3-30 W/l, and maintaining a temperature of from 0 to 60° C. during mixing.