Desoxycyclodepsipeptides and their use for combatting endoparasites

US6355615B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hubert Dyker · Sankt Goarshausen, DE
• Jurgen Scherkenbeck · Leverkusen, DE
• Achim Harder · Leverkusen, DE
• Norbert Mencke · Leverkusen, DE
• Georg von Samson-Himmelstjerna · Solingen, DE

Key dates

• Filing date: Nov 29, 1999
• Grant date: Mar 12, 2002
• Expiry date: Nov 29, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to novel deoxycyclodepsipeptides which are prepared from cyclodepsipeptides having 24 ring members which are constructed from alternating &agr;-aminocarboxylic acids and &agr;-hydroxycarboxylic acids, by complete or partial chemoselective reduction of the carbonyl groups of the amide function to give methylene groups using suitable reduction processes, and to mixtures and derivatives thereof. The deoxycyclodepsipeptides according to the invention have anthelmintic activity.