Guanosine-rich oligonucleotide integrase inhibitors
US6355785B1 · kind B1 · utility
4Cited by
9References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 28, 1999 |
| Grant date | Mar 12, 2002 |
| Priority date | — |
| Expiry date | Oct 28, 2019 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01L2924/0002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and compositions for treating viral infection (IV) vitro and in vivo using a guanosine-rich oligonucleotide. The oligonucleotides have sufficient guanosine to form a guanosine tetrad. Also provided are oligonucleotides of at least two runs of at least two guanosines. Also provided are guanosine-rich oligonucleotides and methods for treating viral infections in humans, and a method for designing guanosine-rich oligonucleotides having anti-viral activity and integrase inhibition activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.