Patent · US Expired

Process for selective reduction

US6355822B1 · kind B1 · utility

2Cited by

1References

9Claims

0Family size

Assignee

DSM Fine Chemicals Austria NFG GmbH & Co KG · AT

Inventors

Dean Vincent Johnson · Graz, AT
Peter Pochlauer · Dordrecht, NL
Herfried Griengl · Graz, AT

Key dates

Filing date	Jul 14, 2000
Grant date	Mar 12, 2002
Priority date	—
Expiry date	Jul 14, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F7/1892
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Process for the stereoselective reduction of chiral &agr;- or &bgr;-keto esters which have a chiral center in the &ggr; position in an inert solvent at temperatures from −80 to +50° C. using a reductant obtained by reaction of NaBH4 and (D)- or (L)-tartaric acid, to give the corresponding diastereomeric hydroxy compounds in each case.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.