Process for preparing 2-cyanoindan-1-ones

US6355827B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Joachim Komoschinski · Neunburg vorm Wald, DE
• Helmut Fiege · Leverkusen, DE
• Guido Steffan · Odenthal, DE

Key dates

• Filing date: Feb 18, 2000
• Grant date: Mar 12, 2002
• Expiry date: Feb 18, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In a particularly advantageous process for producing 2-cyanoindan-1-ones from 2-halogenated indan-1-ones by reaction with a cyanide salt, the cyanide salt is dissolved in a dipolar aprotic solvent or in a water-miscible ether and 2-halogenated indan-1-one is metered into this solution.