Drug release stent coating
US6358556B1 · kind B1 · utility
529Cited by
45References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 23, 1998 |
| Grant date | Mar 19, 2002 |
| Priority date | — |
| Expiry date | Jan 23, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2420/02
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prosthesis are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.