Method for stabilization and renaturation of proteins using nucleolar protein B23
US6358718B1 · kind B1 · utility
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9Claims
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Key dates
| Filing date | Mar 30, 2000 |
| Grant date | Mar 19, 2002 |
| Priority date | — |
| Expiry date | Mar 30, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/96
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods for stabilizing proteins, preventing protein aggregation, renaturation of previously-denatured proteins, reactivating a protein that has been inactivated by denaturation, preserving enzyme activities under conditions of elevated temperatures, inducing thermotolerance in bacteria, increasing the temperature optimum for the activity of an enzyme, and preventing formation of inclusion bodies by bacterially-expressed recombinant proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.