Therapeutic inhibitor of vascular smooth muscle cells
US6358989B1 · kind B1 · utility
56Cited by
165References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 26, 1999 |
| Grant date | Mar 19, 2002 |
| Priority date | — |
| Expiry date | Jul 26, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for inhibiting stenosis or restenosis following vascular trauma in a mammalian host, comprising administering to the host a therapeutically effective dosage of a cytostatic agent and/or cytoskeletal inhibitor so as to biologically stent the traumatized vessel. Also provided is a method to inhibit or reduce vascular remodeling following vascular trauma, comprising administering an effective amount of a cytoskeletal inhibitor. Further provided are pharmaceutical compositions and kits comprising the therapeutic agents of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.