Method for producing glufosinates and intermediate products for the same

US6359162B1 · kind B1 · utility

Assignee

• Hoechst Schering Agrevo GmbH · DE

Inventor

• Lothar Willms · Hillscheid, DE

Key dates

• Filing date: Feb 17, 2000
• Grant date: Mar 19, 2002
• Expiry date: Feb 17, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/3211
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Glufosinate and the 2-methyl analog thereof can be prepared in a multi-step synthesis from methylphosphorus compounds (II) with unsaturated keto compounds (III) via adducts (IV), subsequent reaction under the conditions of a Strecker synthesis and finally hydrolysis of the aminonitrile (V):Step 1: Step 2: Step 3: Hydrolysis of (V) to give glufosinateDepending on process conditions and substrates, various compounds can be identified as adducts (IV).