Thromboresistant coating method
US6361819B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 20, 1999 |
| Grant date | Mar 26, 2002 |
| Priority date | — |
| Expiry date | Aug 20, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31935
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Coatings are provided in which biopolymers may be covalently linked to a substrate. Such biopolymers include those that impart thromboresistance and/or biocompatibility to the substrate, which may be a medical device. Coatings disclosed herein include those that permit coating of a medical device in a single layer, including coatings that permit applying the single layer without a primer. Suitable biopolymers include heparin complexes, and linkage may be provided by a silane having isocyanate functionality. Plasma deposition and solvent swelling techniques are described as preferred methods of depositing a derivatized silane or a silane-heparin coating.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.