Polyhydroxyalkylpyrazine derivatives, their preparation and the medicaments comprising them
US6362185B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2000 |
| Grant date | Mar 26, 2002 |
| Priority date | — |
| Expiry date | Jan 14, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to medicaments comprising at least one compound of formula: whereineither R1 represents a —CH(Ra)—CHOH—CHOH—CH2OH chain andR2 represents a —CH2—CHOH—CHOH—CH2OH chain,or R1 represents a —CHOH—CHF—CHOH—CH2OH chain and R2 represents a —CH2—CHF—CHOH—CH2OH chain,or R1 represents a —CHOH—CHOH—CHOH—Rb chain and R2 represents a —CH2—CHOH—CHOH—Rb chain,or R1 represents a —CH2—CHOH—CHOH—CH2OH chain and R2 represents a —CH2—CHOH—CHOH—CH2OH chain,or R1 and R2 are identical and each represent a —(CHOH)n—CH2OH chain in which n is equal to 1, 2, 3 or 4,Ra represents an alkoxy radical (1-6 C in a straight or branched chain) or a fluorine atom, andRb represents a carboxyl, —CO—NH2 or —CH2—NH2 radical,or one of their stereoisomers or their salts with an inorganic or organic acid, to novel compounds of formula (I) and to their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.