Invivo high throughput toxicology screening method
US6365129B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 27, 1999 |
| Grant date | Apr 2, 2002 |
| Priority date | — |
| Expiry date | Dec 27, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/815
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A high throughput toxicology screening method is provided. In the subject method, at least 10 different compound compositions are tested simultaneously. Each compound composition is tested by contacting it with a plurality, e.g. from about 10 to 1000, of non-mammalian multi-cellular organisms and determining the effect of the compound composition on the organisms. The multi-cellular organisms employed in the subject methods are small, have differentiated tissues and organs and have a rapid generation time. The subject high throughput screening methods find use in a variety of applications, and are particularly suited for use in the toxicology screening of libraries of compounds, such as libraries of combinatorially produced compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.