Contrast agent-enhanced magnetic resonance imaging of tissue perfusion
US6368574B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 21, 2000 |
| Grant date | Apr 9, 2002 |
| Priority date | — |
| Expiry date | Jan 21, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/56341
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to a method of contrast agent-enhanced magnetic resonance imaging of perfusion in vasculated tissue within a human or non-human animal body in which a bolus comprising a contrast-enhancing amount of a magnetic resonance imaging contrast agent is administered into the vascular system of said body, and said body is subjected to a magnetic resonance imaging procedure whereby signals or images representative of first pass of said contrast agent bolus through tissue of interest are generated, characterised in that (i) said contrast agent is capable of exhibiting simultaneous, determinable T1 and T2* reducing effects under the imaging procedure employed and (ii) a T1-weighted imaging procedure is used (a) to visualise the first pass of said contrast agent bolus through said tissue by virtue of its signal lowering T2* effect and (b) to obtain a T1-weighted contrast agent-enhanced image of said tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.