Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
US6368636B1 · kind B1 · utility
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25Claims
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Key dates
| Filing date | Oct 26, 1999 |
| Grant date | Apr 9, 2002 |
| Priority date | — |
| Expiry date | Oct 26, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1358
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of mesenchymal stem cells effective to reduce or inhibit host rejection of the transplant. The mesenchymal stem cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with mesenchymal stem cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.