Reagents and methods useful for detecting diseases of the gastrointestinal tract
US6368792B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 1998 |
| Grant date | Apr 9, 2002 |
| Priority date | — |
| Expiry date | Mar 27, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/136
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS193 and transcribed from GI tract tissue, are described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS193-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS193 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.