Hypoxia mediated neurogenesis
US6368854B2 · kind B2 · utility
18Cited by
1References
3Claims
0Family size
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Key dates
| Filing date | Dec 20, 2000 |
| Grant date | Apr 9, 2002 |
| Priority date | — |
| Expiry date | Dec 20, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are described for the production of neurons or neuronal progenitor cells. Multipotent neural stem cells are proliferated in the presence of growth factors and erythropoietin which induces the generation of neuronal progenitor cells. The erythropoietin may be exogenously applied to the multipotent neural stem cells, or alternatively, the cells can be subjected to hypoxic insult which induces the cells to express erythropoietin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.