Patent · US Expired

Closed antisense and sense oligonucleotides and their applications

US6369038B1 · kind B1 · utility

118Cited by

5References

91Claims

0Family size

Assignee

Genset · FR

Inventors

Marta Blumenfeld · Paris, FR
Pascal Brandys · Suresnes, FR
Luc D'Auriol · Paris, FR
Marc Vasseur · Paris, FR

Key dates

Filing date	Nov 23, 1993
Grant date	Apr 9, 2002
Priority date	—
Expiry date	Nov 23, 2013

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2310/53
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An antisense or sense agent of the oligonucleotide type, includes a single-stranded oligonucleotide sequence having a binding affinity for DNA, RNA, or protein selected from the group consisting of (a) a sequence whose ends are linked to one another via covalent linkage to form a closed, single-stranded structure, and (b) a sequence wherein one free end is linked to an internal nucleotide via covalent linkage to form a closed, single-stranded branched structure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.