Treatment of mastitis
US6369049B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 12, 1999 |
| Grant date | Apr 9, 2002 |
| Priority date | — |
| Expiry date | Apr 12, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D463/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides new fluorinated cephalosporin antibiotics of Formula I whereinRa, Rb, Rc, Rd and Re, independently, are H, F or a C1-C6 alkyl-(Z)n— group having at least one fluorine substituent;X is O or S;Y is S, O, or —CH2—;Z is O, S, —SO—, or —SO2—;m and n independently are 0 or 1; andR1 is H, C1-C6-alkyl, phenyl or benzyl, each of which may optionally have up to three substituents selected from halo, C1-C4-alkoxy, phenyl, NO2, C1-C6-alkanoyl, benzoyl, or C1-C6-alkanoyloxy; or a physiologically acceptable salt thereof;and methods of preventing or treating or treating infection, particularly mastitis in ruminants, using these antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.