Patent · US Expired

Isomerisation of 6&bgr;-fluorosteroids into the corresponding 6&agr;-fluoro derivatives

US6369218B1 · kind B1 · utility

0Cited by
3References
9Claims
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Assignee

Inventors

Key dates

Filing dateMay 16, 2001
Grant dateApr 9, 2002
Priority date
Expiry dateMay 16, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J71/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described herein is the isomerisation process of 6&bgr;-fluorosteroids into the corresponding pharmacologically active 6&agr;-fluoro derivatives, comprising the reaction of 6&bgr;-fluorosteroids, or 6&agr;/6&bgr; isomeric mixtures, with an organic base containing a diazoimino group in a suitable organic solvent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.