Plasticized bioerodible controlled delivery system
US6372245B1 · kind B1 · utility
115Cited by
4References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 22, 1994 |
| Grant date | Apr 16, 2002 |
| Priority date | — |
| Expiry date | Apr 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A controlled release medicament delivery system comprises a plasticized bioerodible polymer, such as a polyorthoester. Medicament desirably is entrapped in the plasticized polymer. The resulting delivery system is able to release the medicament in a controlled and sustained manner. The formulation is particularly advantageous for use as a once-a-day eyedrop. During preparation, the polymer may be heated to an elevated temperature for a sufficient time to substantially reduce its molecular weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.