Palatable, sustained release drug granules
US6372259B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 10, 1999 |
| Grant date | Apr 16, 2002 |
| Priority date | — |
| Expiry date | Nov 10, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1635
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A means and method for manufacturing palatable drug granules using a polymer having at least one free carboxyl group and PVP is described. This is achieved by (1) dissolving/suspending a drug in an aqueous solution of polymers and subsequently adjusting the pH of the solution to an acidic pH or (2) suspending a drug in an organic solution of one of the aforementioned polymers and then adding the other polymer solution, with constant agitation. The polymers form a complex and consequently entraps the drug and produce palatable drug granules that are suitable for preparing sustained release pharmaceutical dosage forms (powders, suspension, tablets, chewable tablets).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.