Patent · US Expired

Nucleic acid molecules encoding Follistatin-3

US6372454B2 · kind B2 · utility

13Cited by
1References
110Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 27, 1998
Grant dateApr 16, 2002
Priority date
Expiry dateAug 27, 2018

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a novel follistatin-3 protein which is a member of the family of inhibin-related proteins. In particular, isolated nucleic acid molecules are provided encoding the human follistatin-3 protein. Follistatin-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of follistatin-3 activity. Also provided are diagnostic methods for detecting reproductive system-related disorders and disorders of the regulation of cell growth and differentiation and therapeutic methods for treating reproductive system-related disorders and disorders of the regulation of cell growth and differentiation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.