Method for controlling the chemical and heat induced responses of collagenous materials
US6375672B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 21, 2000 |
| Grant date | Apr 23, 2002 |
| Priority date | — |
| Expiry date | Mar 21, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2018/00452
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides a method for strengthening collagen in collagenous tissue which uses the controlled application of heat to induce shrinkage or contraction of the collagen in the tissue and a cross-linking means which cross-links the shrunken collagen in the tissue thereby stabilizing and strengthening collagenous tissue. In particular, the present invention provides an in vivo method for treating joint instability problems, controlled manipulation of skin structure and properties, and other problems involving collagen-containing tissues. The present invention further provides an in vitro method for stabilizing collagenous tissue for use in vivo or in vitro. Further, the present invention provides a method for treating collagenous tissue and testing the strength and stability of the treated tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.