Patent · US Expired

Labelled elastase inhibitors

US6375926B1 · kind B1 · utility

14Cited by
2References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 16, 2000
Grant dateApr 23, 2002
Priority date
Expiry dateMay 16, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2123/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A human leucocyte elastase (HLE) inhibitor labelled with a detector moiety where the inhibitor is synthetic and has a molecular weight of less than 2000, is useful for the diagnostic imaging of sites of inflammation of infection in vivo, for labelling leucocytes in vitro, or for radiotherapy of rthritis. The HLE inhibitor is preferably a &bgr;-lactam or an azetidinone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.